In traditional astrology, the fourth house signifies things that you inherit from your family members, your culture, family origin- especially the mothers, how you like your home to look and feel, how you relate to yourself emotionally, heart condition, comforts and luxuries in life, inner peace, and how you were nurtured by the mother.
Supplementing traditional astrology, the esoteric meaning of the fourth house is the foundation of your soul.
Cancer is the original sign ruler of the fourth house and Moon is the traditional planetary ruler. However, if one is dedicated to their spiritual path, the planetary ruler will be Neptune.
Depending on your natal ascendant and planetary placements, your third house signs and planets could be different from the original.